The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008]
Catalog No
A8154
Reactivity
Human, Mouse
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
OXSR1; KIAA1101; OSR1; Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein
Molecular Weight (Da)
58022
Gene Name
OXSR1
Protein Name
Serine/threonine-protein kinase OSR1
Human Gene ID
9943
Human Swiss Prot No.
O95747
Immunogen
The antiserum was produced against synthesized peptide derived from human OSR1 around the phosphorylation site of Thr185. AA range:151-200
Specificity
Phospho-OSR1 (T185) Polyclonal Antibody detects endogenous levels of OSR1 protein only when phosphorylated at T185.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Western blot analysis of lysates from HepG2 cells treated with serum 20% 15', using OSR1 (Phospho-Thr185) Antibody. The lane on the right is blocked with the phospho peptide.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using OSR1 (Phospho-Thr185) Antibody. The picture on the right is blocked with the phospho peptide.
