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ATR (Phospho-Ser428) Antibody
ATR (Phospho-Ser428) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8270
Reactivity:Human,Rat,Mouse
Applications:IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
ATR (Phospho-Ser428) Antibody
Description
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008],
Catalog No
A8270
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
IHC, IF, ELISA
Dilution
IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
ATR; FRP1; Serine/threonine-protein kinase ATR; Ataxia telangiectasia and Rad3-related protein; FRAP-related protein 1
Molecular Weight (Da or kDa)
301kD
Gene Name
ATR
Protein Name
Serine/threonine-protein kinase ATR
Human Gene ID
545
Human Swiss Prot No.
Q13535
Immunogen
The antiserum was produced against synthesized peptide derived from human ATR around the phosphorylation site of Ser428. AA range:394-443
Specificity
Phospho-ATR (S428) Polyclonal Antibody detects endogenous levels of ATR protein only when phosphorylated at S428.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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