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APLP2 (Phospho-Tyr755) Antibody
APLP2 (Phospho-Tyr755) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8292
Reactivity:Human,Mouse,Rat
Applications:IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
APLP2 (Phospho-Tyr755) Antibody
Description
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
Catalog No
A8292
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
IHC, IF, ELISA
Dilution
IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
APLP2; APPL2; Amyloid-like protein 2; APLP-2; APPH; Amyloid protein homolog; CDEI box-binding protein; CDEBP
Molecular Weight (Da or kDa)
87kD
Gene Name
APLP2
Protein Name
Amyloid-like protein 2
Human Gene ID
334
Human Swiss Prot No.
Q06481
Immunogen
The antiserum was produced against synthesized peptide derived from human APLP2 around the phosphorylation site of Tyr755. AA range:714-763
Specificity
Phospho-APLP2 (Y755) Polyclonal Antibody detects endogenous levels of APLP2 protein only when phosphorylated at Y755.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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