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Claudin-6 (Phospho-Tyr219) Antibody
Claudin-6 (Phospho-Tyr219) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8320
Reactivity:Human,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Claudin-6 (Phospho-Tyr219) Antibody
Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010],
Catalog No
A8320
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
CLDN6; Claudin-6; Skullin
Molecular Weight (Da or kDa)
Gene Name
CLDN6
Protein Name
Claudin-6
Human Gene ID
9074
Human Swiss Prot No.
P56747
Immunogen
The antiserum was produced against synthesized peptide derived from human Claudin 6 around the phosphorylation site of Tyr219. AA range:171-220
Specificity
Phospho-Claudin-6 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-6 protein only when phosphorylated at Y219.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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