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Rad50 (Phospho-Ser635) Antibody
Rad50 (Phospho-Ser635) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8409
Reactivity:Human,Rat,Mouse
Applications:WB,IHC
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Rad50 (Phospho-Ser635) Antibody
Description
RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010],
Catalog No
A8409
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC
Dilution
WB 1:500-2000;IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Molecular Weight (Da or kDa)
Gene Name
RAD50
Protein Name
Rad50 (Ser635)
Human Gene ID
10111
Human Swiss Prot No.
Q92878
Immunogen
Synthesized phosho peptide around human Rad50 (Ser635)
Specificity
This antibody detects endogenous levels of Human Rad50 (phospho-Ser635)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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