The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015]
Catalog No
A8452
Reactivity
Human, Mouse, Rat
Applications
WB
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
DNA repair protein XRCC4 (X-ray repair cross-complementing protein 4)
Molecular Weight (Da)
36960
Gene Name
XRCC4
Protein Name
XRCC4 (Phospho-Ser260)
Human Gene ID
7518
Human Swiss Prot No.
Q13426
Immunogen
Synthesized peptide derived from human XRCC4 (Phospho-Ser260)
Specificity
This antibody detects endogenous levels of XRCC4 (Phospho-Ser260) at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, and 0.151% sodium azide.
