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Primary Antibodies
ALK (Phospho-Tyr1586) Antibody
ALK (Phospho-Tyr1586) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8456
Reactivity:Human:Y1586,Mouse:Y1592
Applications:IHC,IF,WB
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

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ALK (Phospho-Tyr1586) Antibody

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Product Details
Product Name
ALK (Phospho-Tyr1586) Antibody
Description
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome
Catalog No
A8456
Reactivity
Human:Y1586, Mouse:Y1592
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
IHC, IF, WB
Dilution
IHC 1:50-200, WB 1:500-2000. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
ALK tyrosine kinase receptor (EC 2.7.10.1; Anaplastic lymphoma kinase; CD antigen CD246)
Molecular Weight (Da or kDa)
Gene Name
ALK
Protein Name
ALK (Phospho-Tyr1586)
Human Gene ID
238
Human Swiss Prot No.
Q9UM73
Immunogen
Synthesized peptide derived from human ALK (Phospho-Tyr1586)
Specificity
This antibody detects endogenous levels of ALK at Human:Y1586; Mouse:Y1592, It doesn't reacte with total protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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