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Primary Antibodies
Rad2/FEN1 (Phospho-Ser187) Antibody
Rad2/FEN1 (Phospho-Ser187) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9114
Reactivity:Human,Mouse,Rat
Applications:WB
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

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Rad2/FEN1 (Phospho-Ser187) Antibody

Western Blot analysis of 1HeLa cell, 2 LPS 100ng/mL 30min treated ,using primary antibody at 1:1000 dilution. Secondary antibody(catalog

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Product Details
Product Name
Rad2/FEN1 (Phospho-Ser187) Antibody
Description
The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage byThe protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions
Catalog No
A9114
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB
Dilution
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1)
Molecular Weight (Da or kDa)
Gene Name
FEN1 RAD2
Protein Name
Rad2/FEN1 (Phospho-Ser187)
Human Gene ID
2237
Human Swiss Prot No.
P39748
Immunogen
Synthesized peptide derived from human Rad2/FEN1 (Phospho-Ser187)
Specificity
This antibody detects endogenous levels of Rad2/FEN1 (Phospho-Ser187) at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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