This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]
Catalog No
A9126
Reactivity
Human, Mouse, Rat
Applications
WB
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Molecular Weight (Da)
167420
Gene Name
TOPBP1 KIAA0259
Protein Name
TOPBP1 (Phospho-Ser1159)
Human Gene ID
11073
Human Swiss Prot No.
Q92547
Immunogen
Synthesized peptide derived from human TOPBP1 (Phospho-Ser1159)
Specificity
This antibody detects endogenous levels of TOPBP1 (Phospho-Ser1159) at Human, Mouse,Rat
Formulation
Liquid in PBS containing 50% glycerol, and 0.168% sodium azide.
