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Primary Antibodies
Cyclin E1 (Phospho-Thr62) Antibody
Cyclin E1 (Phospho-Thr62) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9416
Reactivity:Human,Rat,Mouse
Applications:WB
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Cell Cycle Proteins
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Cyclin E1 (Phospho-Thr62) Antibody

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Product Details
Product Name
Cyclin E1 (Phospho-Thr62) Antibody
Description
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
Catalog No
A9416
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB
Dilution
WB 1:1000-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
G1/S-specific cyclin-E1
Molecular Weight (Da or kDa)
Gene Name
CCNE1 CCNE
Protein Name
Cyclin E1 (Thr62)
Human Gene ID
898
Human Swiss Prot No.
P24864
Immunogen
Synthesized phosho peptide around human Cyclin E1 (Thr62)
Specificity
This antibody detects endogenous levels of Human Cyclin E1 (phospho-Thr62)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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