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TOP2A (Phospho-Ser1213) Antibody
TOP2A (Phospho-Ser1213) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9428
Reactivity:Human,Rat,Mouse
Applications:WB,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
TOP2A (Phospho-Ser1213) Antibody
Description
catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.,miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.,PTM:Phosphorylation has no effect on catalytic activity.,similarity:Belongs to the type II topoisomerase family.,subcellular location:Generally located in the nucleoplasm.,subunit:Homodimer. Interacts with COPS5.,
Catalog No
A9428
Reactivity
Human, Rat, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
DNA topoisomerase 2-alpha (EC 5.99.1.3; DNA topoisomerase II, alpha isozyme)
Molecular Weight (Da or kDa)
Gene Name
TOP2A TOP2
Protein Name
TOP2A (Phospho Ser1213)
Human Gene ID
7153
Human Swiss Prot No.
P11388
Immunogen
Synthesized peptide derived from human TOP2A (Phospho Ser1213)
Specificity
This antibody detects endogenous levels of Human TOP2A (Phospho Ser1213)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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