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FLT3 (Phospho-Tyr591) Antibody
FLT3 (Phospho-Tyr591) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9521
Reactivity:Human,Mouse
Applications:WB
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
FLT3 (Phospho-Tyr591) Antibody
Description
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015],
Catalog No
A9521
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB
Dilution
WB 1:1000-2000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Molecular Weight (Da or kDa)
Gene Name
FLT3 CD135 FLK2 STK1
Protein Name
FLT3 (Tyr591)
Human Gene ID
2322
Human Swiss Prot No.
P36888
Immunogen
Synthesized phosho peptide around human FLT3 (Tyr591)
Specificity
This antibody detects endogenous levels of Human Mouse FLT3 (phospho-Tyr591)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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