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14-3-3σ (Phospho-Ser186) Antibody
14-3-3σ (Phospho-Ser186) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9634
Reactivity:Human,Mouse
Applications:WB,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
14-3-3σ (Phospho-Ser186) Antibody
Description
function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
Catalog No
A9634
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
14-3-3 protein sigma (Epithelial cell marker protein 1; Stratifin)
Molecular Weight (Da or kDa)
Gene Name
SFN HME1
Protein Name
14-3-3σ (Phospho Ser186)
Human Gene ID
2810
Human Swiss Prot No.
P31947
Immunogen
Synthesized peptide derived from human 14-3-3σ (Phospho Ser186)
Specificity
This antibody detects endogenous levels of Human,Mouse 14-3-3σ (Phospho Ser186)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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