Shc (Phospho-Tyr317) Antibody (A9664)

Shc (Phospho-Tyr317) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A9664

Reactivity:Human,Mouse

Applications:WB,ELISA,IHC

Modification:Phospho Specific

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Signaling Intermediates

Buy One Get One

Shc (Phospho-Tyr317) Antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

Delivery

Freight Charges

Utilize our shipping calculator at checkout to view

Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

Promotions

Product Details

Product Name

Shc (Phospho-Tyr317) Antibody

Description

This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],

Catalog No

A9664

Reactivity

Human, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Phospho Specific

Applications

WB, ELISA, IHC

Dilution

WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)

Molecular Weight (Da or kDa)

Gene Name

SHC1 SHC SHCA

Protein Name

Shc (Tyr317)

Human Gene ID

6464

Human Swiss Prot No.

P29353

Immunogen

Synthesized phosho peptide around human Shc (Tyr317)

Specificity