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Primary Antibodies
Insulin R Antibody
Insulin R Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0493
Reactivity:Human,Rat,Mouse,Pig
Applications:IHC,IF,WB,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Insulin R Antibody

Immunofluorescence analysis of HUVEC cells, using IR Antibody. The picture on the right is blocked with the synthesized peptide.

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Product Details
Product Name
Insulin R Antibody
Description
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Catalog No
B0493
Reactivity
Human, Rat, Mouse, Pig
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
IHC, IF, WB, ELISA
Dilution
WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
INSR; Insulin receptor; IR; CD antigen CD220
Molecular Weight (Da or kDa)
Gene Name
INSR
Protein Name
Insulin receptor
Human Gene ID
3643
Human Swiss Prot No.
P06213
Immunogen
The antiserum was produced against synthesized peptide derived from human IR. AA range:1326-1375
Specificity
Insulin R Polyclonal Antibody detects endogenous levels of Insulin R protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (3)
Long Non-coding RNA GAS5 Maintains Insulin Secretion by Regulating Multiple miRNAs in INS-1 832/13 Cells. Frontiers in Molecular Biosciences Front Mol Biosci. 2020; 7: 559267 WB Rat 1:1000 INS-1 832/13 cell

Author: Available in link provided

Date of Publication : Available in link provided

Chronic heat stress increases insulin-like growth factor-1(IGF-1) but does not affect IGF-binding proteins in growing pigs. JOURNAL OF THERMAL BIOLOGY 2018 Aug 18 WB Pig 1:500 Liver

Author: Available in link provided

Date of Publication : Available in link provided

Insulin Attenuates Beta-Amyloid-Associated Insulin/Akt/EAAT Signaling Perturbations in Human Astrocytes. CELLULAR AND MOLECULAR NEUROBIOLOGY Cell Mol Neurobiol. 2016 Aug;36(6):851-864 WB Human 1:500 Astrocytes

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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