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Primary Antibodies
CHOP Antibody
CHOP Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B0863
Reactivity:Human,Mouse
Applications:WB,IHC,IF,ELISA
Modification:Unmodified/Total
Source:Polyclonal,Rabbit,IgG
Storage and Stability:Store at -20°C/1 year

$205
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Tumor Suppressors/Apoptosis
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CHOP Antibody

Immunofluorescence analysis of HeLa cells, using CHOP Antibody. The picture on the right is blocked with the synthesized peptide.

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Product Details
Product Name
CHOP Antibody
Description
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010],
Catalog No
B0863
Reactivity
Human, Mouse
Source
Polyclonal, Rabbit,IgG
Modification
Unmodified/Total
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
DDIT3; CHOP; CHOP10; GADD153; DNA damage-inducible transcript 3 protein; DDIT-3; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; Growth arrest and DNA damage-inducible protein GADD153
Molecular Weight (Da or kDa)
Gene Name
DDIT3
Protein Name
DNA damage-inducible transcript 3 protein
Human Gene ID
1649
Human Swiss Prot No.
P35638
Immunogen
The antiserum was produced against synthesized peptide derived from human CHOP. AA range:15-64
Specificity
CHOP Polyclonal Antibody detects endogenous levels of CHOP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (11)
Perilipin5 protects against lipotoxicity and alleviates endoplasmic reticulum stress in pancreatic β-cells. Nutrition & Metabolism 2019 Jul 30 WB Rat INS-1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2019 Jan 01 WB Human,Mouse lung A549 cell,HBECs

Author: Available in link provided

Date of Publication : Available in link provided

Overexpression of long non‐coding RNA NORAD promotes invasion and migration in malignant melanoma via regulating the MIR‐205‐EGLN2 pathway. Cancer Medicine Cancer Med-Us. 2019 Apr;8(4):1744-1754 WB Human A375 cell, WM35 cell

Author: Available in link provided

Date of Publication : Available in link provided

Sodium fluoride induces apoptosis through reactive oxygen species-mediated endoplasmic reticulum stress pathway in Sertoli cells. Journal of Environmental Sciences 2015 Feb 24 WB Rat Sertoli cell

Author: Available in link provided

Date of Publication : Available in link provided

Mitochondrial pathway and endoplasmic reticulum stress participate in the photosensitizing effectiveness of AE‐PDT in MG63 cells. Cancer Medicine 2016 Oct 03 WB Human MG63 cell

Author: Available in link provided

Date of Publication : Available in link provided

Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E‑/‑ mice by activating autophagy. Molecular Medicine Reports 2015 Jun 16 WB Rat INS-1 cell

Author: Available in link provided

Date of Publication : Available in link provided

Mitochondrial pathway and endoplasmic reticulum stress participate in the photosensitizing effectiveness of AE‐PDT in MG63 cells. Cancer Medicine 2016 Oct 03 WB Human MG63 cell

Author: Available in link provided

Date of Publication : Available in link provided

Cadmium induces liver dysfunction and ferroptosis through the endoplasmic stress-ferritinophagy axis ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY Jiacheng Wu WB Mouse

Author: Available in link provided

Date of Publication : Available in link provided

In Situ Vaccination with Mitochondria-Targeting Immunogenic Death Inducer Elicits CD8+ T Cell-Dependent Antitumor Immunity to Boost Tumor Immunotherapy. Ahu Yuan WB Mouse 4T1 cell

Author: Available in link provided

Date of Publication : Available in link provided

α-Hederin induces human colorectal cancer cells apoptosis through disturbing protein homeostasis. CHEMICO-BIOLOGICAL INTERACTIONS Haibo Cheng WB Human HCT116 cell,SW480 cell

Author: Available in link provided

Date of Publication : Available in link provided

Apigenin improves testosterone synthesis by regulating endoplasmic reticulum stress BIOMEDICINE & PHARMACOTHERAPY Liling Wu WB,ChIP Mouse testicular tissue TM3 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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