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MDM2 Antibody

Catalog No : B1154
  • Reactivity
    Human,Rat,Mouse
  • Applications
    IHC-p,IF/ICC,WB,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Details
  • Product Name
    MDM2 Antibody
  • Description
    This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
  • Catalog No
    B1154
  • Reactivity
    Human, Rat, Mouse
  • Applications
    IHC-p, IF/ICC, WB, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    MDM2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2
  • Molecular Weight (Da)
    55233
  • Gene Name
    MDM2
  • Protein Name
    E3 ubiquitin-protein ligase Mdm2
  • Human Gene ID
    4193
  • Human Swiss Prot No.
    Q00987
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human MDM2. AA range:151-200
  • Specificity
    MDM2 Polyclonal Antibody detects endogenous levels of MDM2 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.