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Primary Antibodies
EDG-1 Antibody
EDG-1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B1180
Reactivity:Human,Mouse,Rat
Applications:WB,IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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EDG-1 Antibody

Western Blot analysis of A549 cells using EDG-1 Polyclonal Antibody

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Product Details
Product Name
EDG-1 Antibody
Description
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Catalog No
B1180
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
S1PR1; CHEDG1; EDG1; Sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P1; Endothelial differentiation G-protein coupled receptor 1; Sphingosine 1-phosphate receptor Edg-1; S1P receptor Edg-1; CD antigen CD363
Molecular Weight (Da)
42696
Gene Name
S1PR1
Protein Name
Sphingosine 1-phosphate receptor 1
Human Gene ID
1901
Human Swiss Prot No.
P21453
Immunogen
The antiserum was produced against synthesized peptide derived from human S1P Receptor EDG1. AA range:206-255
Specificity
EDG-1 Polyclonal Antibody detects endogenous levels of EDG-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (2)
Salidroside Inhibits CCl4-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1

Author: Ye Qiannan, Zhou Yang, Zhao Changqing, Xu Lieming, Ping Jian

Date of Publication : 2021-05-13

Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells

Author: EvaBernharta1SabineDamma1AndreaWinterspergeraChristophNussholdabAnna MartinaBrunneraIoannaPlastiraaGeraldRechbergercHelgaReicheraChristianWadsackdAndreasZimmerbeErnstMallea

Date of Publication : n/a

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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