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Primary Antibodies
p38 Antibody
p38 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: B7179
Reactivity:Human,Mouse,Rat
Applications:IF/ICC,WB,IHC-p,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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p38 Antibody

Western blot analysis of lysates from 293 and RAW246.7 cells, using p38 MAPK Antibody. The lane on the right is blocked with the synthesized peptide.

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Product Details
Product Name
p38 Antibody
Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding d
Catalog No
B7179
Reactivity
Human, Mouse, Rat
Applications
IF/ICC, WB, IHC-p, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
Molecular Weight (Da)
41293
Gene Name
MAPK14
Protein Name
Mitogen-activated protein kinase 14
Human Gene ID
1432
Human Swiss Prot No.
Q16539
Immunogen
The antiserum was produced against synthesized peptide derived from human p38 MAPK. AA range:147-196
Specificity
p38 Polyclonal Antibody detects endogenous levels of p38 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (15)
Polydatin Improves Sepsis-Associated Encephalopathy by Activating Sirt1 and Reducing p38 Phosphorylation

Author: Lin Huang, Jiawei Chen, Xiaojie Li, Mingxin Huang, Jilou Liu, Na Qin, Zhenhua Zeng, Xingmin Wang, Fen Li, Hong Yang

Date of Publication : 2022-04-18

Proliferatins suppress lipopolysaccharide-induced inflammation via inhibition of the NF-κB and MAPK signaling pathways

Author: Qi-xuan Kuang, Qing-zhou Li, Li-rong Lei, Yu-mei Wang, Li-jun Huang, Yi-Fei Dai, Wan Peng, Ming-zhi Zhang, Dong Wang, Yu-cheng Gu, Yun Deng, Da-le Guo

Date of Publication : 2022-04-13

The Apolipoprotein C1 is involved in breast cancer progression via EMT and MAPK/JNK pathway

Author: Hangyu Zhang, Yongfang Wang, Changgang Liu, Wentong Li, Fenghua Zhou, Xinbo Wang, Jie Zheng

Date of Publication : 2021-12-18

P38 MAPK/AKT signalling is involved in IL-33-mediated anti-apoptosis in childhood acute lymphoblastic leukaemia blast cells

Author: Yiqian Wang, Hanyi Hou, Zhongping Liang, Xuexin Chen, Xindan Lian, Jie Yang, Zeyu Zhu, Huanmin Luo, Haibo Su, Qing Gong

Date of Publication : 2021-08-26

Effect of cold stress on the MAPK pathway and lipidomics on muscle of Takifugu fasciatus

Author: Peng Chu, Tao Wang, Yi Ru Sun, Ming Xu Chu, Hong Yu Wang, Xiang Zheng, Shaowu Yin

Date of Publication : 2021-03-26

Interleukin-33 Promotes Cell Survival via p38 MAPK-Mediated Interleukin-6 Gene Expression and Release in Pediatric AML

Author: Yiqian Wang, Haibo Su, Muxia Yan, Li Zhang, Jiancheng Tang, Quanxin Li, Xiaoqiong Gu, Qing Gong

Date of Publication : 2020-11-26

Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo

Author: Yang Sheng Hu, Xu Han, Pei Jing Yu, Ming Ming Jiao, Xin Hua Liu, Jing Bo Shi

Date of Publication : 2020-03-08

Dibromoacetic Acid Induced Hepatotoxicity in Mice through Oxidative Stress and Toll-Like Receptor 4 Signaling Pathway Activation

Author: Gong Tingting, Jiang Wenbo, Gao Zhijian, Chen Yingying, Gao Shuying

Date of Publication : 2019-11-20

β-Conglycinin-Induced Intestinal Porcine Epithelial Cell Damage via the Nuclear Factor κB/Mitogen-Activated Protein Kinase Signaling Pathway

Author: Chenglu Peng, Xuedong Ding, Lei Zhu, Mengchu He, Yingshuang Shu, Yu Zhang, Yu Li, Xichun Wang, Shibin Feng, Jinchun Li, Jinjie Wu

Date of Publication : 2019-07-18

Soybean Glycinin- and β-Conglycinin-Induced Intestinal Damage in Piglets via the p38/JNK/NF-κB Signaling Pathway

Author: Chenglu Peng, Chengming Cao, Mengchu He, Yingshuang Shu, Xuebing Tang, Yuanhong Wang, Yu Zhang, Xiaodong Xia, Yu Li, Jinjie Wu

Date of Publication : 2018-08-24

Astragalus Polysaccharide Inhibits Ionizing Radiation-Induced Bystander Effects by Regulating MAPK/NF-κB Signaling Pathway in Bone Mesenchymal Stem Cells (BMSCs)

Author: Liying Zhang, Yali Luo, Zhiwei Lu, Jinpeng He, Lei Wang, Lixin Zhang, Yiming Zhang, Yongqi Liu

Date of Publication : 2018-07-06

Structural characterization of a pectic polysaccharide from Codonopsis pilosula and its immunomodulatory activities in vivo and in vitro

Author: Pei Zhang, Linhai Hu, Ruibin Bai, Xiaoping Zheng, Yuling Ma, Xia Gao, Bolu Sun, Fangdi Hu

Date of Publication : 2017-06-06

Molecular Mechanisms of IRE1α-ASK1 Pathway Reactions to Unfolded Protein Response in DRN Neurons of Post-Traumatic Stress Disorder Rats

Author: Fanzhen Kong, Fang Han, Yanhao Xu, Yuxiu Shi

Date of Publication : 2017-02-16

Selected lactobacilli strains inhibit inflammation in LPS-induced RAW264.7 macrophages by suppressing the TLR4-mediated NF-κB and MAPKs activation

Author: SHI Jialu, LI Huizhen, LIANG Shengnan, EVIVIE Smith Etareri, HUO Guicheng, LI Bailiang, LIU Fei

Date of Publication : 44638

Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells

Author: Shi Jue, Hu Zihe, Zhou Yanyan, Zuo Minghao, Wu Haiyan, Jin Wenjing, Xie Zhijian

Date of Publication : 44585

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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