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Primary Antibodies
COL2A1 Antibody
COL2A1 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0155
Reactivity:Human,Mouse,Rat
Applications:WB,IHC-p,IF/ICC,ELISA
Modification:Unmodified/Total
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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COL2A1 Antibody

Western Blot analysis of COLO205 cells using COL2A1 Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
COL2A1 Antibody
Description
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
Catalog No
C0155
Reactivity
Human, Mouse, Rat
Applications
WB, IHC-p, IF/ICC, ELISA
Modification
Unmodified/Total
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
COL2A1; Collagen alpha-1(II) chain; Alpha-1 type II collagen
Molecular Weight (Da)
141785
Gene Name
COL2A1
Protein Name
Collagen alpha-1(II) chain
Human Gene ID
1280
Human Swiss Prot No.
P02458
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen II. AA range:101-150
Specificity
COL2A1 Polyclonal Antibody detects endogenous levels of COL2A1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (6)
Atorvastatin inhibited TNF-α induced matrix degradation in rat nucleus pulposus cells by suppressing NLRP3 inflammasome activity and inducing autophagy through NF-κB signaling

Author: Jiancong Chen, Jiansen Yan, Shuangxing Li, Jianxiong Zhu, Jie Zhou, Jun Li, Yangyang Zhang, Zhengqi Huang, Liang Yuan, Kang Xu, Weijian Chen, Wei Ye

Date of Publication : 2021-09-08

Bromodomain-containing protein 7 regulates matrix metabolism and apoptosis in human nucleus pulposus cells through the BRD7-PI3K-YAP1 signaling axis

Author: Shuangxing Li, Zhengqi Huang, Yuanxin Zhu, Jiansen Yan, Jun Li, Jiancong Chen, Jie Zhou, Yangyang Zhang, Weijian Chen, Kang Xu, Wei Ye

Date of Publication : 2021-05-24

Cholesterol Induces Pyroptosis and Matrix Degradation via mSREBP1-Driven Endoplasmic Reticulum Stress in Intervertebral Disc Degeneration.

Author: Yan J, Li S, Zhang Y, Deng Z, Wu J, Huang Z, Qin T, Xiao Y, Zhou J, Xu K, Ye W

Date of Publication : 2021-01-01

The role of SIRT1 in BMP2-induced chondrogenic differentiation and cartilage maintenance under oxidative stress.

Author: Yang Lu, Li Zhou, Lijun Wang, Shan He, Honglei Ren, Nian Zhou, Zhenming Hu

Date of Publication : 2020-05-01

Lycopene alleviates disc degeneration under oxidative stress through the Nrf2 signaling pathway

Author: Yang Lu, Li Zhou, Shan He, Hong-Lei Ren, Nian Zhou, Zhen-Ming Hu

Date of Publication : 2020-03-06

Long non-coding RNA MEG3 inhibits chondrogenic differentiation of synovium-derived mesenchymal stem cells by epigenetically inhibiting TRIB2 via methyltransferase EZH2

Author: Di You, Cheng Yang, Jun Huang, Haoli Gong, Mingming Yan, Jiangdong Ni

Date of Publication : 2019-07-31

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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