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> Products > Primary Antibodies > FGFR-3 Antibody

FGFR-3 Antibody

Overview Description
Datasheet SDS
   Membrane Receptors   
Catalog No : C0192
  • Reactivity
    Human,Mouse,Rat
  • Applications
    WB,IHC-p,IF(paraffin section),ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    FGFR-3 Antibody
  • Description
    This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an Extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a Cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys
  • Catalog No
    C0192
  • Reactivity
    Human, Mouse, Rat
  • Applications
    WB, IHC-p, IF(paraffin section), ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    FGFR3; JTK4; Fibroblast growth factor receptor 3; FGFR-3; CD antigen CD333
  • Molecular Weight (Da)
    87710
  • Gene Name
    FGFR3
  • Protein Name
    Fibroblast growth factor receptor 3
  • Human Gene ID
    2261
  • Human Swiss Prot No.
    P22607
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human FGFR3. AA range:131-180
  • Specificity
    FGFR-3 Polyclonal Antibody detects endogenous levels of FGFR-3 protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western blot analysis of lysates from LOVO cells, using FGFR3 Antibody. The lane on the right is blocked with the synthesized peptide.
Application Data
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FGFR3 Antibody. The picture on the right is blocked with the synthesized peptide.
Application Data
Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Application Data
Western Blot analysis of 3T3 cells using FGFR-3 Polyclonal Antibody diluted at 1:500

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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