Nrf2 Antibody (C0279) | Assay Biotech Inc.

Nrf2 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C0279

Reactivity:Human,Mouse,Rat

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Transcription Regulators

Nrf2 Antibody

Western Blot analysis of HuvEc cells using Nrf2 Polyclonal Antibody diluted at 1:1000

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

Nrf2 Antibody

Description

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]

Catalog No

C0279

Reactivity

Human, Mouse, Rat

Applications

WB, IHC-p, IF/ICC, ELISA

Modification

Unmodified/Total

Source

Polyclonal Rabbit

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

-20°C/1 year

Other Name

NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2, like 2

Molecular Weight (Da)

75-100

Gene Name

NFE2L2

Protein Name

Nuclear factor erythroid 2-related factor 2

Human Gene ID

4780

Human Swiss Prot No.

Q16236

Immunogen

The antiserum was produced against synthesized peptide derived from human Nrf2. AA range:556-605

Specificity

Nrf2 Polyclonal Antibody detects endogenous levels of Nrf2 protein.

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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Publications (21)

Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis

Author: Xie Ting, Chen Xiaodong, Chen Wenyi, Huang Sien, Peng Xinye, Tian Lingmei, Wu Xuejie, Huang Yan

Date of Publication : 2021-12-10

MiR-125b attenuates retinal pigment epithelium oxidative damage via targeting Nrf2/HIF-1α signal pathway

Author: Jin-xia Liu, Dong-yue Ma, Xin-yu Zhi, Ming-wu Wang, Jiang-yue Zhao, Yu Qin

Date of Publication : 2021-12-05

The Keap1/Nrf2-ARE signaling pathway is involved in atrazine induced dopaminergic neurons degeneration via microglia activation

Author: Kun Ma, Hao-Yu Wu, Sheng-Yuan Wang, Bai-Xiang Li

Date of Publication : 2021-10-05

Photodriven nanoreactor with a hydrogen-insulin double act repairs diabetic wounds through Nrf2 pathway activation

Author: Yin Zheng, Zhimin Zhang, Tongcai Wang, Jun Zhang, Dingyuan Tian, Xinge Zhang, Zhongming Wu

Date of Publication : 2021-08-14

Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury

Author: Hui An, Zhenjie Hu, Yuhong Chen, Lianfang Cheng, Jian Shi, Linan Han

Date of Publication : 2021-03-01

A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.

Author: Ke ZB, You Q, Sun JB, Zhu JM, Li XD, Chen DN, Su L, Zheng QS, Wei Y, Xue XY, Xu N

Date of Publication : 2021-01-01

Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy

Author: Shuangwen Li, Lisi Zheng, Jun Zhang, Xuejun Liu, Zhongming Wu

Date of Publication : 2020-11-02

Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose

Author: Yuqian Wang, Xiaoji Cui, Qinlu Lin, Jie Cai, Liuhuan Tang, Ying Liang

Date of Publication : 2020-09-30

Artemisinin attenuates early renal damage on diabetic nephropathy rats through suppressing TGF-β1 regulator and activating the Nrf2 signaling pathway

Author: Haishan Zhang, Simin Qi, Yongchun Song, Cheng Ling

Date of Publication : 2020-06-11

Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways

Author: Qiuping Li, Guifang Wang, Shi Hang Xiong, Yuxue Cao, Baojun Liu, Jing Sun, Lulu Li, Nabijan Mohammadtursun, Hua Yu, Jingcheng Dong, Jinfeng Wu

Date of Publication : 2020-06-10

Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner

Author: Xiao‑Ting Huang, Wei Liu, Yong Zhou, Cai‑Xia Hao, Yan Zhou, Chen‑Yu Zhang, Chen‑Chen Sun, Zi‑Qiang Luo, Si‑Yuan Tang

Date of Publication : 2019-12-01

Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats

Author: Zhang Ling, Fan Xin-Rong, Xie Hui, He Qing-Hu, Nie Yu-Song, Zhang Min, Yan Miao

Date of Publication : 2018-06-26

Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis

Author: Shi-Hai Yan, Ning-Wei Zhao, Zhi-Rong Geng, Jia-Yin Shen, Fu-Ming Liu, Dong Yan, Jie Zhou, Chao Nie, Cheng-Cai Huang, Zhu-Yuan Fang

Date of Publication : 2017-12-06

Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo

Author: Rong Shen, Disheng Liu, Chenchen Hou, Di Liu, Lixia Zhao, Ju Cheng, Degui Wang, Decheng Bai

Date of Publication : 2017-08-15

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

Author: Wang Xing-he, Cui Xiao-xu, Sun Xiao-qi, Wang Xing-hui, Li Xiao-chong, Qi Yue, Li Wei, Han Mei-yu, Muhammad Ishfaq, Zhang Xiu-ying

Date of Publication : 2017-05-15

Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals

Author: Heba-Alla H. Abd-ElSalam, Medhat A. Al-Ghobashy, Muhammad Al-Shorbagy, Noha Nassar, Hala E. Zaazaa, Mohamed A. Ibrahim

Date of Publication : 2016-06-08

Glycogen Synthase Kinase 3β Influences Injury Following Cerebral Ischemia/Reperfusion in Rats

Author: Yixin Li, Jin Zhu, Yuanling Liu, Xi Chen, Shipeng Lei, Lingyu Li, Beibei Jiang, Li Tan, Shanshan Yu, Yong Zhao

Date of Publication : 2016-02-29

GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion

Author: Chen, Xi, Liu, Yuanling, Zhu, Jin, Lei, Shipeng, Dong, Yuan, Li, Lingyu, Jiang, Beibei, Tan, Li, Wu, Jingxian, Yu, Shanshan, Zhao, Yong

Date of Publication : 2016-02-03

Glutamine ameliorates intestinal ischemia-reperfusion Injury in rats by activating the Nrf2/Are signaling pathway

Author: Ai-Li Wang, Qiong Niu, Ning Shi, Jian Wang, Xing-Fang Jia, Hai-Feng Lian, Zhiqiang Liu, Cheng-Xia Liu

Date of Publication : 2015-07-01

DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia

Author: Liao, Tingting, Xu, Xia, Ye, Xu, Yan, Jianying

Date of Publication : 44613

An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule.

Author: Huxinyue Duan, Meiyan Li, Jia Liu, Jiayi Sun, Chunjie Wu, Yu Chen, Xiaohui Guo，Xinglong Liu

Date of Publication : 44608

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Catalog No: C0279

Reactivity:Human,Mouse,Rat

Applications:WB,IHC-p,IF/ICC,ELISA

Modification:Unmodified/Total

Source:Polyclonal Rabbit

Storage and Stability:-20°C/1 year

Nrf2 Antibody

IRAK-1 (Phospho-Thr209) Antibody

COL1A2 Antibody

SYP Antibody

TNF-α Antibody

β-actin Monoclonal Antibody(5B7)

GAPDH Monoclonal Antibody(2B8)

HRP* Goat Anti Mouse IgG(H+L)

HRP* Goat Anti Rabbit IgG(H+L)

Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis

MiR-125b attenuates retinal pigment epithelium oxidative damage via targeting Nrf2/HIF-1α signal pathway

The Keap1/Nrf2-ARE signaling pathway is involved in atrazine induced dopaminergic neurons degeneration via microglia activation

Photodriven nanoreactor with a hydrogen-insulin double act repairs diabetic wounds through Nrf2 pathway activation

Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury

A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer.

Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy

Active Peptide KF-8 from Rice Bran Attenuates Oxidative Stress in a Mouse Model of Aging Induced by d-Galactose

Artemisinin attenuates early renal damage on diabetic nephropathy rats through suppressing TGF-β1 regulator and activating the Nrf2 signaling pathway

Bu-Shen-Fang-Chuan formula attenuates cigarette smoke-induced inflammation by modulating the PI3K/Akt-Nrf2 and NF-κB signalling pathways

Dihydroartemisinin attenuates lipopolysaccharide‑induced acute lung injury in mice by suppressing NF‑κB signaling in an Nrf2‑dependent manner

Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats

Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis

Protective effect of Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity in vitro and in vivo

High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals

Glycogen Synthase Kinase 3β Influences Injury Following Cerebral Ischemia/Reperfusion in Rats

GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion

Glutamine ameliorates intestinal ischemia-reperfusion Injury in rats by activating the Nrf2/Are signaling pathway

DJ-1 upregulates the Nrf2/GPX4 signal pathway to inhibit trophoblast ferroptosis in the pathogenesis of preeclampsia

An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule.

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