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> Products > Primary Antibodies > DAN Antibody

DAN Antibody

Overview Description
Datasheet SDS
   Growth Factors and Hormones   
Catalog No : C10599
  • Reactivity
    Human,Rat,Mouse
  • Applications
    WB,IHC-p,IF/ICC,ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Storage and Stability
    -20°C/1 year
  • Size
    50 μl
  • Price/Quantity
    $205
  • Quantity
Add to Cart
Details
  • Product Name
    DAN Antibody
  • Description
    This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]
  • Catalog No
    C10599
  • Reactivity
    Human, Rat, Mouse
  • Applications
    WB, IHC-p, IF/ICC, ELISA
  • Modification
    Unmodified/Total
  • Source
    Polyclonal Rabbit
  • Dilution
    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration
    1 mg/ml
  • Storage and Stability
    -20°C/1 year
  • Other Name
    NBL1; DAN; DAND1; Neuroblastoma suppressor of tumorigenicity 1; DAN domain family member 1; Protein N03; Zinc finger protein DAN
  • Molecular Weight (Da)
    19277
  • Gene Name
    NBL1
  • Protein Name
    Neuroblastoma suppressor of tumorigenicity 1
  • Human Gene ID
    4681
  • Human Swiss Prot No.
    P41271
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human NBL1. AA range:131-180
  • Specificity
    DAN Polyclonal Antibody detects endogenous levels of DAN protein.
  • Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Application Data
Western blot analysis of lysates from Jurkat and COLO cells, using NBL1 Antibody. The lane on the right is blocked with the synthesized peptide.
Application Data
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using NBL1 Antibody. The picture on the right is blocked with the synthesized peptide.
Application Data
Immunofluorescence analysis of HeLa cells, using NBL1 Antibody. The picture on the right is blocked with the synthesized peptide.
Application Data
Western Blot analysis of various cells using DAN Polyclonal Antibody diluted at 1:500

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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