DHRS4 Antibody (C15323) | Assay Biotech Inc.

DHRS4 Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C15323

Reactivity:Human,Rat,Mouse

Applications:WB,IHC,IF,ELISA

Modification:Unmodified/Total

Source:Polyclonal,Rabbit,IgG

Storage and Stability:Store at -20°C/1 year

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

Synthesis and Degradation

DHRS4 Antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using DHRS4 Antibody. The picture on the right is blocked with the synthesized peptide.

Delivery

Freight Charges

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

Telephone

408-747-0185

Fax

408-747-0145

order@assaybiotech.com

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Product Details

Product Name

DHRS4 Antibody

Description

catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,function:Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.,miscellaneous:Inhibited by kaempferol, quercetin, genistein and myristic acid.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subcellular location:Isoform 1 is peroxisomal, while isoform 4 is not.,subunit:Homotetramer.,tissue specificity:Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoforms 5 and 6 are expressed in a few neoplastic cervical tissues.,

Catalog No

C15323

Reactivity

Human, Rat, Mouse

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

WB, IHC, IF, ELISA

Dilution

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

DHRS4; Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD

Molecular Weight (Da or kDa)

Gene Name

DHRS4

Protein Name

Dehydrogenase/reductase SDR family member 4

Human Gene ID

10901

Human Swiss Prot No.

Q9BTZ2

Immunogen

The antiserum was produced against synthesized peptide derived from human DHRS4. AA range:191-240

Specificity