Rag A/B Antibody (C18211) | Assay Biotech Inc.

Rag A/B Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: C18211

Reactivity:Human,Mouse,Rat

Applications:WB,IHC,IF,ELISA

Modification:Unmodified/Total

Source:Store at -20°C/1 year

Storage and Stability:

Size:

Price/Quantity $205

Quantity:

Datasheet

SDS

GDP/GTP Binding Proteins

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Rag A/B Antibody

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Delivery

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

Rag A/B Antibody

Description

function:Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.,subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein.,tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.,

Catalog No

C18211

Reactivity

Human, Mouse, Rat

Source

Polyclonal, Rabbit,IgG

Modification

Unmodified/Total

Applications

WB, IHC, IF, ELISA

Dilution

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Storage and Stability

Store at -20°C/1 year

Other Name

RRAGA; Ras-related GTP-binding protein A; Rag A; RagA; Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1; RRAGB; Ras-related GTP-binding protein B; Rag B; RagB

Molecular Weight (Da or kDa)

Gene Name

RRAGA/RRAGB

Protein Name

Q7L523 / Q5VZM2

Human Gene ID

The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313

Human Swiss Prot No.

Rag A/B Polyclonal Antibody detects endogenous levels of Rag A/B protein.

Immunogen

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity