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Primary Antibodies
pVHL (AB1587) Mouse mAb (Ready to Use)
pVHL (AB1587) Mouse mAb (Ready to Use)

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0120R
Species Reactivity:Human
Application:Immunohistochemistry (IHC)
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$70
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# SDS #
Ready to Use Antibodies
Immunohistochemistry
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pVHL (AB1587) Mouse mAb (Ready to Use)

Human malignant melanoma tissue was stained with anti-S100A4 (AB1589) Antibody

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Product Details
Product Name
pVHL (AB1587) Mouse mAb (Ready to Use)
Description
pVHL (Von Hippel- Lindau protein) , with a molecular weight of approximately 30 kDa, is a tumor suppressor protein encoded by the VHL gene. Its primary function is to regulate intracellular protein degradation, particularly in relation to the hypoxia- inducible factor (HIF) . pVHL is a crucial tumor suppressor that influences angiogenesis, metabolism, and tumor growth by modulating HIF degradation. Mutations in the VHL gene are the main driving factor of clear cell renal cell carcinoma (ccRCC) and are closely associated with hereditary diseases such as Von Hippel- Lindau disease. Pathological detection of pVHL and related targeted therapies play a significant role in cancer diagnosis and treatment.
Catalog No
V0120R
Species Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Modifcation
No Modification
Clone
AB1587
Isotype
IgG2b, kappa
Application
Immunohistochemistry (IHC)
Application Dilutions
It has been optimized for direct use, requiring no further dilution.
Immunogen
A synthetic peptide corresponding to the amino acid region 150 - 213 of the human pVHL protein.
Specificity
The antibody can specifically recognize human pVHL protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Purification
Immunogen affinity purified
Subcellular Location
Cytoplasmic
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
VHL
Gene ID
7428
Human swiss
P40337
Protein Name
pVHL
Synonyms
von Hippel-Lindau disease tumor suppressor, Protein G7, pVHL
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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