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Primary Antibodies
MLH1 (AB2477) Mouse mAb
MLH1 (AB2477) Mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0499
Species Reactivity:Human
Application:WB,ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$150
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MLH1 (AB2477) Mouse mAb

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Product Details
Product Name
MLH1 (AB2477) Mouse mAb
Description
The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) .
Catalog No
W0499
Species Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB2477
Isotype
IgG1, kappa
Application
WB, ELISA
Application Dilutions
WB, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
Recombinant protein of human MLH1.
Specificity
This antibody detects endogenous levels of MLH1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol and 0.05% proclin300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
MLH1
Gene ID
4292
Human swiss
P40692
Protein Name
MLH1
Synonyms
FCC2; COCA2; HNPCC; MLH-1; hMLH1; HNPCC2; LYNCH2; MMRCS1; H1
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Primary Antibodies

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