PMEL/Melanoma gp100 (HMB45) (AB1395) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0417

Species Reactivity:Human; Mouse;

Application:IHC; WB; IF; ELISA

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

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PMEL/Melanoma gp100 (HMB45) (AB1395) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

PMEL/Melanoma gp100 (HMB45) (AB1395) mouse mAb

Description

PMEL is a type I transmembrane glycoprotein which is specific in malanocyte. PMEL is abundantly expressed in melanosomes, and plays a central role in the biogenesis of melanosomes by involved in the maturation of melanosomes from stage I to II. It is highly expressed in all stages of melanoma progression, so the PMEL antibody can specifically labels melanoma cells.

Catalog No

W0417

Species Reactivity

Human; Mouse;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1395

Isotype

IgG1, kappa

Application

IHC; WB; IF; ELISA

Application Dilutions

IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 500 of the human PMEL/Melanoma gp100 protein.

Specificity

The antibody can specifically recognize human PMEL protein.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein G affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

PMEL

Gene ID

6490

Human swiss

P40967

Protein Name

PMEL/Melanoma gp100

Synonyms

95 kDa melanocyte specific secreted glycoprotein, 95 kDa melanocyte-specific secreted glycoprotein, D12S53E, gp100, M-beta, ME20, ME20 M/ME20 S, ME20-M, ME20-S, ME20M, ME20M/ME20S, ME20S, Melanocyte lineage specific antigen GP100, Melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocyte protein Pmel 17 precursor, Melanocytes lineage-specific antigen GP100, Melanoma associated ME20 antigen, Melanoma gp100, Melanoma-associated ME20 antigen, Melanosomal matrix protein 17, Melanosomal matrix protein17, P1, p100, p26, PMEL 17, PMEL, PMEL_HUMAN, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SI, SIL, SILV, Silver (Mouse homolog) like, Silver homolog, Silver locus protein homolog, Silver, Mouse, homolog of