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p27Kip1 (AB1572) mouse mAb
p27Kip1 (AB1572) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0384
Species Reactivity:Human;
Application:IHC; WB; IF; ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
p27Kip1 (AB1572) mouse mAb
Description
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4) . [provided by RefSeq, Apr 2014],
Catalog No
W0384
Species Reactivity
Human;
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB1572
Isotype
IgG1, kappa
Application
IHC; WB; IF; ELISA
Application Dilutions
IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 198 of the human p27Kip1 protein.
Specificity
This antibody detects endogenous levels of p27Kip1 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDKN1B
Gene ID
1027
Human swiss
P46527
Protein Name
p27Kip1
Synonyms
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1, p27
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