MutS Protein Homolog 6 (MSH6) (AB1562) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0367

Species Reactivity:Human;

Application:IHC; WB; IF; ELISA

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

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MutS Protein Homolog 6 (MSH6) (AB1562) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

MutS Protein Homolog 6 (MSH6) (AB1562) mouse mAb

Description

MSH6 is an important gene in the human mismatch repair gene family, which is located at position 16 of the p arm of chromosome 2. Human mismatch repair genes play an important role in maintaining the integrity and stability of genetic information and avoiding genetic mutation. The deletion of this gene after mutation will make the cell mismatch repair function defective, lead to microsatellite instability (MSI) , and make the tumor susceptible. Clinically, it is often used in the screening of Lynch syndrome together with mismatch repair proteins MLH1, MSH2 and PMS2.

Catalog No

W0367

Species Reactivity

Human;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1562

Isotype

IgG1, kappa

Application

IHC; WB; IF; ELISA

Application Dilutions

IHC, 1:100-1:500 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

A synthetic peptide corresponding to the amino acid region 900 - 1000 of the human MutS Protein Homolog 6 protein.

Specificity

The antibody can specifically recognize human MSH6 protein. In western blotting of HEK293 cell lysate, the antibody can label a 180 kDa band corresponding to MSH6, while there is no band detected in MSH6 knock out HEK293 cell lysate.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein G affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

MSH6

Gene ID

2956

Human swiss

P52701

Protein Name

MutS Protein Homolog 6

Synonyms

DNA mismatch repair protein Msh6, G/T mismatch binding protein, G/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC 5, HNPCC5, HSAP, MSH 6, MSH6, MSH6_HUMAN, mutS (E. coli) homolog 6, MutS alpha 160 kDa subunit, MutS homolog 6 (E. coli) , mutS homolog 6, MutS-alpha 160 kDa subunit, p160, Sperm associated protein