COX-2 (AB1537) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0336

Species Reactivity:Human;

Application:IHC; WB; IF; ELISA

Host:Mouse

Clonality:Monoclonal

Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

Size:

Price/Quantity $135

Quantity:

Datasheet

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COX-2 (AB1537) mouse mAb

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Lead Time

Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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408-747-0185

Fax

408-747-0145

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Product Details

Product Name

COX-2 (AB1537) mouse mAb

Description

COX has two isomeric forms of COX-1 and COX-2. It is a membrane-bound protease involved in the conversion of arachidonic acid to prostaglandins. COX-2 is an inducible enzyme that participates in the expression of cell growth factors, tumor promoting factors and cytokines, and is highly expressed in breast, lung, and colon cancers. It is mainly used in tumor research and is one of the targets of tumor therapy.

Catalog No

W0336

Species Reactivity

Human;

Clonality

Monoclonal

Host

Mouse

Modifcation

Unmodified

Clone

AB1537

Isotype

IgG2b, kappa

Application

IHC; WB; IF; ELISA

Application Dilutions

IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.

Immunogen

A synthetic peptide corresponding to the amino acid region 500 - 604 of the human COX - 2 protein.

Specificity

The antibody can specifically recognize human COX-2 protein. In western blotting of Hela and A549 cell lysates, the antibody can label a 70 kDa band corresponding to COX-2.

Formulation

The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.

Purification

The antibody was purified by protein G affinity chromatography.

Storage and Stability

Store at-20℃. Avoid freeze / thaw cycles.

Gene Name

PTGS2

Gene ID

5743

Human swiss

P35354

Protein Name

COX-2

Synonyms

COX 2, COX-2, COX2, Cyclooxygenase 2, Cyclooxygenase 2b, Cyclooxygenase, Cyclooxygenase-2, Cyclooxygenase2, EC 1. 14. 99. 1, fj02a10, Glucocorticoid-regulated inflammatory cyclooxygenase, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, GRIPGHS, hCox 2, Macrophage activation-associated marker protein P71/73, OTTHUMP00000033524, PES-2, PGG/HS, PGH synthase 2, PGH2_HUMAN, PGHS 2, PGHS-2, PGHS2, PHS 2, PHS II, PHS2, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) , Prostaglandin endoperoxide synthase 2, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 2 precursor, Prostaglandin G/H synthase and cyclooxygenase, Prostaglandin G/H synthase, Prostaglandin H2 synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) , Prostaglandin-endoperoxide synthase 2, PTGS2, ptgs2a, TIS10, TIS10 protein, unp1239, wu:fj02a10