25% Off Select Antibodies and ELISA Kits
Sign In/Register 0

We use cookies, check our Privacy Policies.

p15 INK (AB2442) mouse mAb
p15 INK (AB2442) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: W0139
Species Reactivity:Human;
Application:WB; IF; ELISA
Host:Mouse
Clonality:Monoclonal
Storage and Stability:Store at-20℃. Avoid freeze / thaw cycles.

$135
Product Details
Product Name
p15 INK (AB2442) mouse mAb
Description
cyclin dependent kinase inhibitor 2B (CDKN2B) Homo sapiens This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008],
Catalog No
W0139
Species Reactivity
Human;
Clonality
Monoclonal
Host
Mouse
Modifcation
Unmodified
Clone
AB2442
Isotype
IgG
Application
WB; IF; ELISA
Application Dilutions
WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Immunogen
A synthetic peptide corresponding to the amino acid region 50 - 138 of the human p15 INK protein.
Specificity
This antibody detects endogenous levels of p15 INK protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Purification
The antibody was purified by protein G affinity chromatography.
Storage and Stability
Store at-20℃. Avoid freeze / thaw cycles.
Gene Name
CDKN2B
Gene ID
1030
Human swiss
P42772
Protein Name
p15 INK
Synonyms
Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2 (MTS-2) , p14-INK4b, p15-INK4b (p15INK4B) , CDKN2B, MTS2
Related Products