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Stat5b Monoclonal Antibody
Stat5b Monoclonal Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N0598
Reactivity:Human
Applications:WB,ELISA
Modification:Unmodfied/ Total
Source:Monoclonal Mouse
Storage and Stability:-20°C/1 year

$210
Product Details
Product Name
Stat5b Monoclonal Antibody
Description
signal transducer and activator of transcription 5B(STAT5B) Homo sapiens. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provi
Catalog No
N0598
Reactivity
Human
Applications
WB,ELISA
Modification
Unmodfied/ Total
Source
Monoclonal Mouse
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification
Affinity purification
Concentration
Storage and Stability
-20°C/1 year
Other Name
STAT5B; Signal transducer and activator of transcription 5B
Molecular Weight (Da)
Gene Name
STAT5B
Protein Name
Signal transducer and activator of transcription 5B
Human Gene ID
6777
Human Swiss Prot No.
P51692
Immunogen
Purified recombinant fragment of human Stat5b expressed in E. Coli.
Specificity
Stat5b Monoclonal Antibody detects endogenous levels of Stat5b protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
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