Apolipoprotein B(APOB) Homo sapiens This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008],
Catalog No
NA0008
Reactivity
Human,Mouse
Applications
FCM,ELISA
Modification
Not Modification Specific
Source
Nano-antibody with his-tag, Camel
Dilution
ELISA 1:10000-20000
Purification
The antibody was affinity-purified nickel column using his-tag in antibody
