This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Catalog No
D12076
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Forkhead box protein O4 (Fork head domain transcription factor AFX1)
Molecular Weight (Da)
Gene Name
FOXO4 AFX AFX1 MLLT7
Protein Name
Forkhead box protein O4 (Fork head domain transcription factor AFX1)
Human Gene ID
4303
Human Swiss Prot No.
P98177
Immunogen
Synthetic Acetyl peptide from human protein at AA range: 189
Specificity
The antibody detects endogenous FoxO4 when Acetyl occurs at Lys189
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Western blot analysis of 3T3 mouse-kidney KB K562 Hela lysate, antibody was diluted at 500. Secondary antibody(catalogNo.:SA0002) was diluted at 1:20000
