This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]
Catalog No
D12218
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Myoblast determination protein 1 (Class C basic helix-loop-helix protein 1) (bHLHc1) (Myogenic factor 3) (Myf-3)
Molecular Weight (Da)
35200
Gene Name
MYOD1 BHLHC1 MYF3 MYOD
Protein Name
MyoD (Acetyl Lys99/K102)
Human Gene ID
4654
Human Swiss Prot No.
P15172
Immunogen
Synthesized peptide derived from human MyoD (Acetyl Lys99/K102)
Specificity
This antibody detects endogenous levels of Human MyoD (Acetyl Lys99/K102)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.