This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]
Catalog No
D12227
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1) (High mobility group protein R)
Molecular Weight (Da)
11770
Gene Name
HMGA1 HMGIY
Protein Name
HMG-I/HMG-Y (Acetyl Lys15)
Human Gene ID
3159
Human Swiss Prot No.
P17096
Immunogen
Synthesized peptide derived from human HMG-I/HMG-Y (Acetyl Lys15)
Specificity
This antibody detects endogenous levels of Human, Mouse, Rat HMG-I/HMG-Y (Acetyl Lys15)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
