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Histone H4 (Acetyl-Lys16) Antibody
Histone H4 (Acetyl-Lys16) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12251
Reactivity:Human,Mouse,Rat
Applications:IF,WB,IHC,
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Histone H4 (Acetyl-Lys16) Antibody

Immunofluorescence analysis of human-lung tissue. 1,Histone H4 (Acetyl Lys16) Polyclonal Antibody(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 50min).3, Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B

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Product Details
Product Name
Histone H4 (Acetyl-Lys16) Antibody
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015],
Catalog No
D12251
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
IF, WB, IHC,
Dilution
IF 1:50-200 WB 1:1000-2000 IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
Storage and Stability
Store at -20°C/1 year
Other Name
HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK; HIST2H4A; H4/N; H4F2; H4FN; HIST2H4; HIST2H4B; H4/O; H4FO; HIST4H4; Histone H4; H4k16AC
Molecular Weight (Da or kDa)
Gene Name
HIST1H4A
Protein Name
Histone H4
Human Gene ID
121504
Human Swiss Prot No.
P62805
Immunogen
Synthetic Peptide of Histone H4 (Acetyl Lys16)
Specificity
The antibody detects endogenous Histone H3 (Acetyl Lys16) protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
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Publications (1)
Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy. Journal of Hematology & Oncology J Hematol Oncol. 2018 Dec;11(1):1-16 WB Human DLD-1 cell, SW480 cell

Author: Available in link provided

Date of Publication : Available in link provided

Primary Antibodies

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    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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