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Primary Antibodies
Bcl-6 (Acetyl-Lys379) Antibody
Bcl-6 (Acetyl-Lys379) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12252
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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Bcl-6 (Acetyl-Lys379) Antibody

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Product Details
Product Name
Bcl-6 (Acetyl-Lys379) Antibody
Description
disease:A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.,disease:A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.,disease:Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.,function:Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.,induction:Down-regulated during maturation of dendritic cells by selective stimuli such as LPS, CD40L and zymosan.,PTM:Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with ZBTB7 and BCL6B (By similarity). Interacts with the catalytic domain of HDAC9.,tissue specificity:Expressed in germinal center T and B cells and in primary immature dendritic cells.,
Catalog No
D12252
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
B-cell lymphoma 6 protein (BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51)
Molecular Weight (Da or kDa)
Gene Name
BCL6 BCL5 LAZ3 ZBTB27 ZNF51
Protein Name
Bcl-6 (Acetyl Lys379)
Human Gene ID
604
Human Swiss Prot No.
P41182
Immunogen
Synthesized peptide derived from human Bcl-6 (Acetyl Lys379)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Bcl-6 (Acetyl Lys379)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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