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Primary Antibodies
FoxO1A (Acetyl-Lys245) Antibody
FoxO1A (Acetyl-Lys245) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12260
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
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FoxO1A (Acetyl-Lys245) Antibody

Western Blot analysis of HEK 293 cells, cell treated or untreated by TSA 400nM 24h. Primary Antibody was diluted at 1:1000. Secondary antibody(catalog

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Product Details
Product Name
FoxO1A (Acetyl-Lys245) Antibody
Description
disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2) [MIM:268220]; also known as alveolar rhabdomyosarcoma. Translocation (2;13)(q35;q14) with PAX3; translocation t(1;13)(p36;q14) with PAX7. The resulting protein is a transcriptional activator.,function:Transcription factor.,PTM:Phosphorylated by AKT1; insulin-induced (By similarity). IGF1 rapidly induces phosphorylation of Ser-256, Thr-24, and Ser-319. Phosphorylation of Ser-256 decreases DNA-binding activity and promotes the phosphorylation of Thr-24, and Ser-319, permitting phosphorylation of Ser-322 and Ser-325, probably by CK1, leading to nuclear exclusion and loss of function. Phosphorylation of Ser-329 is independent of IGF1 and leads to reduced function. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 fork-head DNA-binding domain.,subcellular location:Shuttles between cytoplasm and nucleus.,subunit:Interacts with LRPPRC.,tissue specificity:Ubiquitous.,
Catalog No
D12260
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Forkhead box protein O1 (Forkhead box protein O1A; Forkhead in rhabdomyosarcoma)
Molecular Weight (Da or kDa)
Gene Name
FOXO1 FKHR FOXO1A
Protein Name
FoxO1A (Acetyl Lys245)
Human Gene ID
2308
Human Swiss Prot No.
Q12778
Immunogen
Synthesized peptide derived from human FoxO1A (Acetyl Lys245)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat FoxO1A (Acetyl Lys245)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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