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Primary Antibodies
Histone H2A.Z (Acetyl-Lys14) Antibody
Histone H2A.Z (Acetyl-Lys14) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: D12277
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Modification:Acetyl Specific
Source:Store at -20°C/1 year
Storage and Stability:

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Histone H2A.Z (Acetyl-Lys14) Antibody

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Product Details
Product Name
Histone H2A.Z (Acetyl-Lys14) Antibody
Description
function:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.,mass spectrometry:Monoisotopic, not modified PubMed:16457589,PTM:Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis.,PTM:Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression.,PTM:Not phosphorylated.,similarity:Belongs to the histone H2A family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2AFZ forms an heterodimer with H2B. H2AFZ interacts with INCENP.,
Catalog No
D12277
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Acetyl Specific
Applications
WB, ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
Histone H2A.Z (H2A/z)
Molecular Weight (Da or kDa)
Gene Name
H2AFZ H2AZ
Protein Name
Histone H2A.Z (Acetyl Lys14)
Human Gene ID
3015
Human Swiss Prot No.
P0C0S5
Immunogen
Synthesized peptide derived from human Histone H2A.Z (Acetyl Lys14)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Histone H2A.Z (Acetyl Lys14)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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