Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
Catalog No
D12285
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
Modification
Acetyl Specific
Source
Polyclonal Rabbit
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
Histone H2B type 1-A (Histone H2B, testis) (Testis-specific histone H2B)
Molecular Weight (Da)
13970
Gene Name
HIST1H2BA TSH2B
Protein Name
Histone H2B (Acetyl Lys17)
Human Gene ID
255626
Human Swiss Prot No.
Q96A08
Immunogen
Synthesized peptide derived from human Histone H2B (Acetyl Lys17)
Specificity
This antibody detects endogenous levels of Human,Mouse,Rat Histone H2B (Acetyl Lys17)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
