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Primary Antibodies
Cleaved-Caspase-3 p12 (D175) Antibody
Cleaved-Caspase-3 p12 (D175) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: L0105
Reactivity:Human,Rat,Mouse
Applications:WB,IF/ICC,IHC-p,ELISA
Modification:Cleaved Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Cleaved-Caspase-3 p12 (D175) Antibody

Western Blot analysis of KB cells using Cleaved-Caspase-3 p12 (D175) Polyclonal Antibody diluted at 1:1000

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Product Details
Product Name
Cleaved-Caspase-3 p12 (D175) Antibody
Description
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Catalog No
L0105
Reactivity
Human, Rat, Mouse
Applications
WB, IF/ICC, IHC-p, ELISA
Modification
Cleaved Specific
Source
Polyclonal Rabbit
Dilution
WB 1:500-2000, IHC-p 1:50-300, IF 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Molecular Weight (Da)
31608
Gene Name
CASP3
Protein Name
Caspase3
Human Gene ID
836
Human Swiss Prot No.
P42574
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 3. AA range:157-206
Specificity
Cleaved-Caspase-3 p12 (D175) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-3 p12 protein resulting from cleavage adjacent to D175.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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