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Primary Antibodies
Ku-70 (Phospho-Ser5) Antibody
Ku-70 (Phospho-Ser5) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0449
Reactivity:Human,Mouse
Applications:WB,IHC-p,IF(paraffin section),ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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Tumor Suppressors/Apoptosis
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Ku-70 (Phospho-Ser5) Antibody

Western blot analysis of lysates from HeLa cells, using Ku70 (Phospho-Ser5) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
Ku-70 (Phospho-Ser5) Antibody
Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Catalog No
A0449
Reactivity
Human, Mouse
Applications
WB, IHC-p, IF(paraffin section), ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
Molecular Weight (Da)
69843
Gene Name
XRCC6
Protein Name
X-ray repair cross-complementing protein 6
Human Gene ID
2547
Human Swiss Prot No.
P12956
Immunogen
The antiserum was produced against synthesized peptide derived from human Ku70 around the phosphorylation site of Ser5. AA range:1-50
Specificity
Phospho-Ku-70 (S5) Polyclonal Antibody detects endogenous levels of Ku-70 protein only when phosphorylated at S5.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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