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ALK (Phospho-Tyr1507) Antibody
ALK (Phospho-Tyr1507) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0611
Reactivity:Human,Mouse,Monkey
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
ALK (Phospho-Tyr1507) Antibody
Description
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome
Catalog No
A0611
Reactivity
Human, Mouse, Monkey
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
ALK; ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD antigen CD246
Molecular Weight (Da or kDa)
Gene Name
ALK
Protein Name
ALK tyrosine kinase receptor
Human Gene ID
238
Human Swiss Prot No.
Q9UM73
Immunogen
The antiserum was produced against synthesized peptide derived from human ALK around the phosphorylation site of Tyr1507. AA range:1473-1522
Specificity
Phospho-ALK (Y1507) Polyclonal Antibody detects endogenous levels of ALK protein only when phosphorylated at Y1507.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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