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Primary Antibodies
LAT (Phospho-Tyr200) Antibody
LAT (Phospho-Tyr200) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0669
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

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LAT (Phospho-Tyr200) Antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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Product Details
Product Name
LAT (Phospho-Tyr200) Antibody
Description
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Catalog No
A0669
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC
Dilution
WB 1:500-2000;IHC 1:50-300
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
LAT; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; pp36; p36-38
Molecular Weight (Da or kDa)
Gene Name
LAT
Protein Name
Linker for activation of T-cells family member 1
Human Gene ID
27040
Human Swiss Prot No.
O43561
Immunogen
The antiserum was produced against synthesized peptide derived from human LAT around the phosphorylation site of Tyr171. AA range:171-220
Specificity
Phospho-LAT (Y200) Polyclonal Antibody detects endogenous levels of LAT protein only when phosphorylated at Y200.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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