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Primary Antibodies
LKB1 (Phospho-Ser428) Antibody
LKB1 (Phospho-Ser428) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A0672
Reactivity:Human,Mouse,Cow
Applications:WB,IHC-p,IF/ICC,ELISA
Modification:Phospho Specific
Source:Polyclonal Rabbit
Storage and Stability:-20°C/1 year

$205
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LKB1 (Phospho-Ser428) Antibody

Western blot analysis of lysates from HeLa cells treated with PMA 125ng/ml 30', using LKB1 (Phospho-Ser428) Antibody. The lane on the right is blocked with the phospho peptide.

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Product Details
Product Name
LKB1 (Phospho-Ser428) Antibody
Description
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Catalog No
A0672
Reactivity
Human, Mouse, Cow
Applications
WB, IHC-p, IF/ICC, ELISA
Modification
Phospho Specific
Source
Polyclonal Rabbit
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
-20°C/1 year
Other Name
STK11; LKB1; PJS; Serine/threonine-protein kinase STK11; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19
Molecular Weight (Da)
48636
Gene Name
STK11
Protein Name
Serine/threonine-protein kinase STK11
Human Gene ID
6794
Human Swiss Prot No.
Q15831
Immunogen
The antiserum was produced against synthesized peptide derived from human LKB1 around the phosphorylation site of Ser428. AA range:384-433
Specificity
Phospho-LKB1 (S428) Polyclonal Antibody detects endogenous levels of LKB1 protein only when phosphorylated at S428.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Publications (1)
Virus-mediated decrease of LKB1 activity in the mPFC diminishes stress-induced depressive-like behaviors in mice

Author: Wen-Qian Tang, Yue Liu, Chun-Hui Ji, Jiang-Hong Gu, Yan-Mei Chen, Jie Huang, Wei Guan, Da-Wei Xu, Bo Jiang

Date of Publication : 2021-12-27

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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