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Lamin A/C (Phospho-Ser22) Antibody
Lamin A/C (Phospho-Ser22) Antibody

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: A8464
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF,ELISA
Modification:Phospho Specific
Source:Store at -20°C/1 year
Storage and Stability:

$205
Product Details
Product Name
Lamin A/C (Phospho-Ser22) Antibody
Description
lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012],
Catalog No
A8464
Reactivity
Human, Mouse, Rat
Source
Polyclonal, Rabbit,IgG
Modification
Phospho Specific
Applications
WB, IHC, IF, ELISA
Dilution
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Storage and Stability
Store at -20°C/1 year
Other Name
LMNA; LMN1; Prelamin-A/C
Molecular Weight (Da or kDa)
Gene Name
LMNA
Protein Name
Prelamin-A/C
Human Gene ID
4000
Human Swiss Prot No.
P02545
Immunogen
The antiserum was produced against synthesized peptide derived from human Lamin A around the phosphorylation site of Ser22. AA range:2-51
Specificity
Phospho-Lamin A/C (S22) Polyclonal Antibody detects endogenous levels of Lamin A/C protein only when phosphorylated at S22.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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